---
title: "Patient Education: Paliperidone (Invega)"
description: Learn about Paliperidone (Invega), its uses, dosing, potential side effects, and when to seek medical attention for your child or adolescent's mental health treatment.
image: https://blog.mindweal.com/hubfs/20.png
---

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# Patient Education: Paliperidone (Invega)

---

[Paliperidone](https://blog.mindweal.com/blog/tag/paliperidone) [Invega](https://blog.mindweal.com/blog/tag/invega) [MD10001335354](https://blog.mindweal.com/blog/tag/md10001335354)

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Paliperidone is prescribed by your healthcare provider based on current guidelines to address specific mental health conditions. While effective, all medications have potential side effects. It's crucial to be informed about these risks and benefits. It's also important to understand strategies to reduce their occurrence or manage them effectively. It's vital to know when to contact your healthcare provider or seek immediate medical attention. This guide aims to empower you with this knowledge, ensuring a well-informed approach to your child's treatment. If you are still unsure, always reach out to your healthcare provider for further guidance.

 

![Group-9747](https://blog.mindweal.com/hs-fs/hubfs/Group-9747.png?width=56&height=50&name=Group-9747.png)

## What is Paliperidone?

![divider](https://blog.mindweal.com/hs-fs/hubfs/divider.png?width=120&height=5&name=divider.png)

Paliperidone belongs to a group of medicines known as Second Generation or Atypical Antipsychotics. It is the active metabolite of risperidone, meaning it is a derivative of risperidone.

 

### **![IMAGE-36-553x1024-1](https://blog.mindweal.com/hs-fs/hubfs/IMAGE-36-553x1024-1.png?width=309&height=572&name=IMAGE-36-553x1024-1.png)**

### **When is Paliperidone prescribed to Children & Adolescents? **

Your doctor may prescribe Paliperidone for: 

- Behavioral disturbances or Disruptive Mood Dysregulation Disorder (also known as DMDD)
- Bipolar disorder
- Autism-related irritability
- Psychosis
- Tics or Tourette’s Syndrome

 

 

 

 

 

### **What is the Dose of Paliperidone?**

- **Oral Tablets**: The typical dose ranges from 3 to 9 mg per day.
- **Monthly Depot Injection (Invega Sustenna)**: The dose ranges from 39 mg to 234 mg per month.
- **3-Month Depot Injection (Invega Trinza)**: The dose ranges from 273 mg to 819 mg every 3 months.

Paliperidone is usually started at a low dose, gradually increasing to reach an effective level.

## ![afterHourCRisis (1)](https://blog.mindweal.com/hs-fs/hubfs/afterHourCRisis%20(1).png?width=70&height=71&name=afterHourCRisis%20(1).png)

## **What can be the possible**

## **side-effects from the medication?**

Common Side-Effects

Less Common Side-Effects

Uncommon Side-Effects

- **Tiredness, dizziness:**

- - Might occur initially but usually improves.
    - Started at a low dose to minimize effects.
    - Consult with your provider if persistent.

- **Increased appetite and weight gain:**

- - More likely at higher doses.
    - Can lead to risks like high blood pressure, increased total and bad cholesterol, and diabetes.
    - Regular monitoring of weight, waist size, blood pressure, blood sugar, and cholesterol is important.
    - Monitor your child’s diet and inform your doctor of significant weight gain.

- **Increase Prolactin levels (Hyperprolactinemia)**

- - Watch for breast development in boys, menstrual changes in girls and nipple discharge in both the genders
    - Your provider will order labs every 6 months to check prolactin levels, to monitor for this side-effect closely.
    - Prolactin levels should be checked every 6-12 months.
    - Stopping medication typically normalizes levels. ***Note: breast development in boys may not be reversible.***

- **Drooling:** 
    - Due to excessive saliva production.
    - Consult with your provider if persistent. Adjustment in medication may be necessary.

 

- **Dystonia: **

- - Symptoms include involuntary muscle contractions leading to unusual postures, such as neck twisting, back arching. 
    - Seek emergency care if these occur. Medications (Benadryl or Benztropine) may be used for relief.

- **Akathisia: **

- - Intense inner restlessness, possibly manifesting as excessive physical activity or anxiety.
    - Management may involve adjusting dosage or medication, or adding another medication (beta-blocker)

- **Heart Rhythm Disturbances: **

- - QTc prolongation, a condition that lengthens the heart's electrical cycle, may lead to irregular heartbeats.
    - If you notice an irregular heartbeat, inform your healthcare provider.
    - Stopping or changing the medication might be required.

- **Tardive Dyskinesia (TD):**  
    - Characterized by involuntary, repetitive body movements.
    - Regular monitoring with the Abnormal Involuntary Movement Scale (AIMS) is essential.

### ![Group-10151](https://blog.mindweal.com/hs-fs/hubfs/Group-10151.png?width=84&height=79&name=Group-10151.png)

## Serious but Rare Side-Effects

 

**![IMAGE-37-553x1024](https://blog.mindweal.com/hs-fs/hubfs/IMAGE-37-553x1024.png?width=311&height=576&name=IMAGE-37-553x1024.png)**

 

 

 

- **Neuroleptic malignant syndrome**

 

 

 

To learn more about this medication, please visit MedlinePlus, an official US government website, part of the National Library of Medicine and managed by National Institute of Health. Click [**HERE**](https://medlineplus.gov/druginfo/meds/a607005.html)for information on oral Paliperidone and [**HERE**](https://medlineplus.gov/druginfo/meds/a615032.html) for information on Paliperidone injection.

 

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