Patient Education: Asenapine (Saphris)

Asenapine is prescribed by your healthcare provider based on current guidelines to address specific mental health conditions. While effective, all medications have potential side effects. It's crucial to be informed about these risks and benefits. It's also important to understand strategies to reduce their occurrence or manage them effectively. It's vital to know when to contact your healthcare provider or seek immediate medical attention. This guide aims to empower you with this knowledge, ensuring a well-informed approach to your child's treatment. If you are still unsure, always reach out to your healthcare provider for further guidance.

What is Asenapine?

Asenapine belongs to a group of medicines known as Second Generation or Atypical Antipsychotics.

When is Asenapine prescribed to Children & Adolescents? 

Your doctor may prescribe Asenapine for

• Behavioral disturbances or Disruptive Mood Dysregulation Disorder (also known as DMDD)
• Irritability associated with autism spectrum disorder 
• Bipolar disorder
• Psychosis

What is the Dose of Asenapine?

• The dose typically ranges from 2.5mg twice a day to 10mg twice a day
• Place the tablet under your tongue and let it dissolve completely. Do not chew or swallow the tablet.
• Do not eat or drink anything for at least 10 minutes after taking the medication to ensure it is fully absorbed.
• Started at a low dose, gradually increased to effectiveness.

What can be the possible

side-effects from the medication?

Serious but Rare Side-Effects

• Neuroleptic malignant syndrome

• Symptoms: High fever, severe muscle stiffness, changes in blood pressure, heart rate, and breathing.
• Action Required: Immediately discontinue medication and seek urgent medical care in a hospital.
• Treatment: Immediate medical care in a hospital.

To learn more about this medication please visit MedlinePlus, a official US government website, part of National Library of Medicine and managed by National Institute of Health by clicking HERE